Leveraging of our TAM base editing technology, exon skipping drugs are developed.
GEN6050, our first product, is designed to treat DMD patients amenable to exon 50 skipping. Promising results have been observed in initial animal experiments and human iPSC cell studies, demonstrating the product’s effectiveness and safety. We are now leveraging the experience gained from GEN6050 to advance other products.
Senior pharmacology and toxicology advisor
Pharmacology, Shang University of Traditional Chinese Medicine.
Senior Vice General Manager at Shanghai InnoStar Biotechnology Co., Ltd.
More than 20 years in preclinical pharmacology and toxicology evaluation of new drugs.
Senior Scientific Advisor
Ph.D., Molecular Cell Biology and Bioengineering, Max Planck Research School.
Senior Director of genome engineering department, AstraZeneca, Gothenburg, Sweden.
More than 10 years’ experience in gene editing tool and drug development.
Senior Clinical Physician Advisor
Ph.D. , Peking Union Medical College, Tsinghua University.
Associate Chief physician. Neurology Department. Peking Union Medical College Hospital, Beijing.
Member of the Neurology Branch of the Chinese Medical Association.
Member of the DMD/BMD Study Group of the Chinese Rare Disease Alliance.
Specializes in complex and rare neurological disorders, gene diagnosis of monogenic.
Senior strategic Advisor
Over 30 years of experience in drug discovery, clinical translation, clinical practice, and operational management Former President of Chongqing Medical and Pharmaceutical College.
Ex-Vice President of the Technical Center at Fosun Pharma.
Senior Biostatistics Advisor
Ph.D. Biostatistics, University of Michigan, USA.
Bettyann Asche Murray Distinguished Professor, Deputy Chair.
Department of Biostatistics, University of Texas, MD Anderson Cancer Center.
Inventor of Bayesian Optimal lnterval PhaseⅠ/ⅡTrial Design (BOlN12); Participated in clinical trial design of many anti-cancer treatment.
Co-funder, Senior scientific Advisor
Ph.D. , Pathology, Ohio State University
Associate Professor at West Lake University, Young Scientist in the 973 Program
Thousand Youth Talents Program, National Outstanding Young Scientist
Inventor of Targeted AID-mediated Mutagenesis (TAM) base editor
CEO, Co-Founder
Ph.D. , Immunology, Shanghai Jiao Tong University.
MBA, Manchester Business School.
Over 20 years of experience in pharmaceutical industry, covering R&D, BD, Investment and Incubation.
Quality management advisor
Former Director of the Quality Assurance Department and Laboratory at the Shanghai Institute of Biological Products
Research and establishment of quality standards for various viral bioproducts as well as registration applications
Committee Member of the Chinese Pharmacopoeia Commission,
Expert Member of the Shanghai Science and Technology Commission
Committee Member of the Quality Management Committee of the Shanghai Medical Industry Association
Member of the New Technology/Skills Professional Committee.